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Hangzhou Worlde. ……0. MIDI Port. 0. 2ad HUMAX Co., Ltd. PVR Mass Storage. MM3. 00 e. Book Reader. OCZ Technology Inc. OCZ ATV USB 2. 0 Flash Drive. OCZ Rally. 2/ATV USB 2. Flash Drive. 0. 32. OCZ Technology Inc. ATV Turbo / Rally. Dual Channel USB 2. Flash Drive. ……0. PSX for USB Converter. Shenzhen Sinote Tech- Electron Co., Ltd. SE3. 40. D PC Remote Control. Bernd Walter Computer Technology. HD4. 47. 80 LCD interface. End. Points, Inc. SE4. 01 Webcam. ……0. Ethernet [klsi]. ……0. ATAPI Enclosure. ……2. Si. Pix Style. Cam Deluxe. Aox 9. 90. 01. 0. Thesys Microelectronics. Data Broadcasting Corp. Atmel Corp. ……0. 90. Port Hub. ……2. 00. Mass Storage Device. HID keyboard). ……2. CDC ACM). ……2. 01. HID mouse). ……2. 01d at. HID generic). ……2. LUFA Test PID. ……2. LUFA Mouse Demo Application. LUFA Keyboard Demo Application. LUFA Joystick Demo Application. LUFA CDC Demo Application. LUFA Mass Storage Demo Application. LUFA Audio Output Demo Application. LUFA Audio Input Demo Application. LUFA MIDI Demo Application. Stripe Snoop Magnetic Stripe Reader. LUFA CDC Class Bootloader. LUFA USB to Serial Adapter Project. LUFA RNDIS Demo Application. LUFA Combined Mouse and Keyboard Demo Application. LUFA Dual CDC Demo Application. LUFA Generic HID Demo Application. Benito Programmer Project. LUFA Combined Mass Storage and Keyboard Demo Application. LUFA Combined CDC and Mouse Demo Application. LUFA Datalogger Device. Interfaceless Control- Only LUFA Devices. LUFA Test and Measurement Demo Application. LUFA Multiple Report HID Demo. LUFA Virtual Serial/Mass Storage Demo. LUFA Webserver Project. JTAG ICE mk. II. ……2. AVR ISP mk. II. ……2. AVRONE! ……2. 10. 6 STK6. AVR Dragon. ……2. 10. STK5. 41 Zig. Bee Development Board. XPLAIN evaluation kit (CDC ACM). AVR JTAGICE3 Debugger and Programmer. XMEGA- A1 Explained evaluation kit. ICE debugger. ……2. EVK1. 1xx evaluation board. ATxmega. 32. A4. U DFU bootloader. Cactus V6 (DFU). ……2fea Cactus RF6. DFU). ……2ff. 0 atmega. 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CD- R/RW. ……ffff Dongle with Blue. Core in DFU mode. Hewlett- Packard. Desk. Jet 8. 95c. Office. Jet G5. 5. Desk. Jet 1. 12. 5C Printer Port. KU- 0. 31. 6 Keyboard. Laser. Jet P1. 10. Scan. Jet 4. 10. 0c. Photo. Smart S2. 0. Desk. Jet 8. 80c/9. Scan. Jet 4. 20. 0c. CD- Writer Plus. ……0. Multimedia Keyboard Hub. G5. 5xi Printer/Scanner/Copier. Laser. Jet 3. 20. Adapter. ……0. 11d Bluetooth 1. Interface [Broadcom BCM2. HP4. 9g+ Calculator. HID Internet Keyboard. Barcode Scanner 4. Scan. Jet 6. 20. 0c. Photo. Smart S2. 0. Desk. Jet 8. 15c. Scan. Jet 3. 30. 0c. CD- Writer Plus 8. Multimedia Keyboard. Office. Jet G8. 5. Desk. Jet 1. 22. 0C. Laser. Jet 2. 20. APOLLO P2. 50. 0/2. Laserjet CP1. 52. Link- 5 micro dongle. Desk. Jet 8. 10c/8. Scan. Jet 4. 30. 0c. CD- Writer+ CD- 4e. Office. Jet G8. 5xi. Color Inkjet CP1. Laser. Jet 1. 20. SK- 2. 88. 5 keyboard. Elite Keyboard. ……0. Scan. Jet 5. 20. 0c. Desk. Jet 8. 30c/8. Scan. Jet 3. 40. 0cse. Office. Jet G9. 5. Printing Support. Laser. Jet 1. 20. HS- COMBO Cardreader. Laser. Jet M1. 13. MFP. ……0. 44. 1 HP Prime Calculator. Desk. Jet 8. 85c. Scan. Jet 2. 10. 0c. Wireless Keyboard. Office. Jet K6. 0. Deck. Jet 4. 50. ……0. Laser. Jet 1. 00. Bluetooth Interface. Scan. Jet 6. 30. 0c. Desk. Jet 8. 40c. Scan. Jet 2. 20. 0c. Office. Jet K6. 0xi. Bluetooth Dongle. Scan. Jet 5. 30. 0c/5. Desk. Jet 8. 25c. Scan. Jet 4. 40. 0c. Office. Jet K8. 0. Desk. Jet 1. 18. 0c. Printing Support. Scan. Jet 7. 40. 0c. Desk. Jet 8. 16c. HP4. 47. 0C. ……0. Office. Jet K8. 0xi. Laser. Jet 3. 30. Scan. Jet 2. 30. 0c. Desk. Jet 8. 45c. Printing Support. Laser. Jet 3. 33. Modular Smartcard Keyboard. Optical Mouse [6. Scan. Jet 2. 40. 0c. Laser. Jet 3. 70. Scan. Jet 8. 2x. 0C. Wireless Keyboard and Optical Mouse receiver. Laser. Jet 2. 30. Laser. Jet 1. 01. Bluetooth Dongle. Office. Jet 9. 10. Laser. Jet 1. 01. Laser. Jet 1. 01. Wireless Keyboard and Optical Mouse receiver. Office. Jet V4. 0. Printing Support. Laser. Jet 1. 15. Laser. 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Scan. Jet 5. 53. 0C Photo. Smart. ……1. 61. 1 psc 7. Laser. Jet 3. 01. Wireless Rechargeable Optical Mouse (HID). Smart Card Keyboard – JP. Photo. Smart 3. 80 series. Desk. Jet 9. 48. C. Scan. Jet 5. 59. 0. Printing Support. Laser. Jet 3. 02. Bluetooth 2. 0 Interface [Broadcom BCM2. Inkjet P- 2. 00. 0U. Photo. Smart 4. 70 series. Desk. Jet 9. 16. C. Scan. Jet 7. 65. 0. PSC 7. 20. ……1. 81. Office. Jet Pro K5. Laser. Jet 3. 03. Bluetooth 2. 0 Interface. Photo. Smart A4. 30 series. Desk. Jet 3. 82. 0. Office. Jet V4. 5. Laser. Jet 3. 38. Photo. Smart A5. 10 series. Office. Jet 5. 10. Laser. Jet 4. 65. Photo. Smart A6. 10 series. Desk. Jet 3. 81. 0. Scan. Jet 4. 85. 0C/4. C. ……1b. 07 Premium Starter Webcam. Photo. Smart A7. 10 series. Color Laser. Jet 2. Photo. Smart A3. 10 series. Laser. Jet 1. 32. Barcode scanner. ……1e. Photo. Smart A3. 20 Printer series. PSC- 9. 50. ……1e. Laser. Jet 1. 16. Photo. Smart A4. 40 Printer series. PSC 9. 20. ……1f. 12 Office. Jet Pro K5. 30. 0. Laser. Jet 5. 55. Gobi Wireless Modem. Desk. Jet 6. 40c. Scan. Jet 3. 57. 0c. Office. Jet Pro K5. Gobi Wireless Modem (QDL mode). Cashdrawer. ……2. 10. Photo. Smart 7. 34. Desk. Jet 6. 30c. Office. Jet Pro L7. Sierra MC5. 72. 5 [ev. Photo. Smart 7. 60. Scan. Jet 3. 50. 0c. Office. Jet Pro L7. Laser. Jet 9. 50. MFP. ……2. 30. 2 Photo. Smart 7. 60. 0 series. Desk. Jet 6. 56c. Scan. Jet 3. 97. 0c. Office. Jet d series. Office. Jet Pro L7. Laser. Jet 4. 35. Broadcom 2. 07. 0 Bluetooth Combo. Photo. Smart 7. 70. Deskjet F2. 28. 0 series. Scan. Jet 4. 07. 0 Photo. Smart. ……2. 41. 7 Laser. Jet 4. 25. 0. ……2. Gobi 2. 00. 0 Wireless Modem (QDL mode). LP1. 96. 5 1. 9″ Monitor Hub. Photo. Smart 7. 70. Desk. Jet F4. 20. Scan. Jet 3. 77. 0. Office. Jet Pro L7. Compaq LA2. 40. 5 series monitor. Laser. Jet 2. 41. Gobi 2. 00. 0 Wireless Modem. LP3. 06. 5 3. 0″ Monitor Hub. Photo. Smart A5. 20 series. Scan. Jet 3. 80. 0c. Office. Jet 7. 10. Color Laser. Jet 2. Pole Display (HP5. Line Display). ……2. Photo. Smart A6. 20 series. Desk. Jet 9. 15. ……2. Color Laser. Jet 2. Magnetic Stripe Reader IDRA- 3. HP. ……2. 80. 5 Scanjet G2. PSC- 2. 10. 0. ……2. Color Laser. Jet 2. Photo. Smart A8. 20 series. PSC 2. 20. 0. ……2. Laser. Jet 2. 42. PSC 2. 15. 0 series. Laser. Jet 2. 43. PSC 2. 17. 0 series. Laser. Jet 1. 02. Officejet J4. 68. Laser. Jet 1. 02.
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Free and open- source, but usually bundled with proprietary apps and drivers[3][4]Proprietary except for open source components. Proprietary. Proprietary. Free and open- source, but the SDK is proprietary and closed source. Free and open- source, but the UI is proprietary and closed source. OS family. Linux. Darwin. Windows 1. Mobile. QNXLinux. Linux. Supported CPU architecture. ARM, x. 86, MIPS and the 6. ARM6. 4ARMARMARM, x. ARM, x. 86- 6. 4Programmed in. C, C++, Java, . NET C# (Xamarin)C, C++, Objective- C, Swift, . NET C# (Xamarin)7+: XNA (. NET C#), Silverlight, native C/C++ (only for vendors and partners[5])8+: . NET C#, VB. NET, Silverlight, native C/C++, Win. RTP (XMLA), Direct. XC/ C++: Native SDK, C++/Qt: Cascades SDK, HTML5/Javascript/CSS: Webworks SDK, Action. Script: Adobe AIR, Java: Android runtime. C++C++, QML, Python. Public issues list. Yes[7]No[8]Yes[9]Yes[1. Yes[1. 1]DRM- free[1. No[1. 3] since Android 4. Android 4. 3[1. 5] and more restrictions on Android 4. No - Fair. Play. No. No[1. 7]Yes. Yes. Device independent system updates. Partial system updates since Oreo[1. Lineage. OS[1. 9]Yes[2. Only for developers. No. No. Yes. Wireless system updates. Yes. 5+[2. 1]8+[2. Yes[2. 3]No. Yes. GPU accelerated GUI3+[2. Yes. Yes[2. 5]Yes, OS 7. Yes. Feature. Androidi. OSWindows 1. 0 Mobile. Black. Berry 1. 0Tizen. Sailfish OSAdvanced controls[edit]App ecosystem[edit]App ecosystem. Feature. Androidi. OSWindows 1. 0 Mobile. Black. Berry 1. 0Tizen. Sailfish OSOfficial app store. Google Play. App Store. Windows Store. Black. Berry World, Amazon Appstore[9. Tizen Store. Jolla Store. Non- discriminatory stores. No, Some apps like Ad blockers are censored on Google Play[9. No, Apple discriminates based on country[9. Apple policies[9. No, Discriminates by country,[9. Openrepos.[9. 9] Developers can distribute apps from their own sources, supports multiple app stores. Common APIs for smartphones, tablets, and PCs. Yes[1. 00]Smartphone and tablet only[1. No. No. Yes. Official SDK platform(s)Linux, Mac OS X and Windows[1. Mac OS X using i. OS SDKWindows[1. 04]Windows, Mac OS X,[1. Linux (only Native SDK for 1. GNU/Linux, Windows, OS X[1. Windows, Mac OS X and Linux[1. Cost to develop for the mobile OSFree. Free with Xcode 7[1. Free[1. 10]Free. Free. Free. Cost to publish app to official store. US$2. 5 once to offer it on Google Play[1. US$9. 9/year. US$1. Students can get a token for an individual account (1 token for 3. Windows Store/Phone Dev Center for 1. Free. Free. Free[1. Basic features[edit]Basic features. Feature. Androidi. OSWindows 1. 0 Mobile. Black. Berry 1. 0Tizen. Sailfish OScut, copy, and paste. Yes[1. 15]3+[1. 16]Yes[1. Yes. Yes[1. 18]Partially released[1. Multi- Device clipboard. No. 10+[1. 20]No. No. No. Noundo. No[1. No. No. No. No[1. Custom home and lock screen wallpaper. Yes. 4+[6. 4]Yes. Yes. Yes. Yes (incl. Ambience)Desktop sync. No,[1. 24] but available on Samsung Kies & HTC Sense[1. Yes. Yes. Yes. Yes? Local full backup. Limited backup for 4. ADB using external computer. Possible with 3rd party apps with rooted phones or a custom recovery[1. Yes, using external computer[1. No, removed in WP8,[1. WP7 in Zune only when performing update, or anytime via 3rd party software[1. Yes, using external computer[1. No[1. 33]Yes. Core data missing sync. Bookmarks[1. 34] (before 4), SMSs and Settings[1. Favorites,[1. 36] Text Messages[1. Settings[1. 38]??? Notification center. Yes. 5+[1. 39]8. 1+[8. Yes. Push notifications. Yes[1. 42]Yes (Apple Push Notification Service)Yes[1. Yes. 2+[1. 44]Yes. Screenshot. 4+ also available on earlier versions with customized roms, such as Cyanogen Mod and the default Samsung Galaxy S II rom[1. Yes[6. 4][1. 46]8+[1. Yes. 2. 0. 2+[1. 49]i. Calendar import. No,[1. Yes[1. 52]3rd party software (only import not subscribe)[1. Yes[1. 54]? 1. 1. Text/document support (read only; creating using third party apps)Microsoft Office Mobile, PDF, TXT/RTFMicrosoft Office,[1. Work, PDF, Images, TXT/RTF, VCFMicrosoft Office 2. PDF, Images, TXT/RTFMicrosoft Office, PDF, Open. Document, TXTRead only: text files, PDF, HTML, Multiple office formats. Microsoft Office, Open. Document, PDFPrinter support. Google Cloud Print[1. USB[1. 60]Yes (Air. Print)[1. 61]1. 0+[1. Yes. No? Show remembered Wi- Fi connections. Yes. No, 3rd party software on jailbroken devices[1. Yes. Yes? Yes. Browser[edit]Browser. Feature. Androidi. OSWindows 1. 0 Mobile. Black. Berry 1. 0Tizen. Sailfish OSDefault web browser/engine. Blink. Web. Kit. Trident (Edge. HTML after 1. 0)Web. Kit. Web. Kit. Gecko[1. Major web browser available. Chrome for Android, Opera, Firefox. Safari, Chrome for i. OS, Opera Mini, Firefox. Internet Explorer, Opera Mini, UC Browser, Microsoft Edge. Black. Berry 1. 0 Browser, Opera Mini, Firefox. Tizen Browser (Based on UC Browser)Sailfish Browser (Firefox), Webcat (Web. Kit), Web Pirate (Web. Kit), others via Android (Firefox, Chrome, Opera)Browser extensions. No[1. 65] 3rd party software[1. No, 3rd party software[1. No. No. No. Browser direct Internet connection (increased resilience to outages)Yes. Yes. Yes. 10+,[1. Black. Berry Internet Service, direct browsing supported over Wi. Fi. Yes? Browser undo close tab. Google Chrome for Android[1. No. No. No. No. Browser keeps windows open on shutdown or crash. Google Chrome[1. 72] but not on main browser[1. Yes. Yes. 10+ Opens dialog for choosing which websites to restore after crash, option to restore all sites after restart. No. Yes. Browser keeps windows open when cleaning cookies. Yes. 3rd party software[1. Yes. Yes? Yes. Browser search engine options. Many[1. 75]Bing, Google, Yahoo! Search, Duck. Duck. Go. Bing, Google support removed on some markets on 8. GDR1+[1. 76]W1. 0M: Many. Bing, Dictionary. Google, Wikipedia, Yahoo, User Defined. Bing, Google, Yahoo! Search. Bing, Google, Yahoo, Yandex. Baidu, Duck. Duck. Go, Start. Page, Searx, ixquick, Swisscows, Qwant, Seznam, Hulbee via openrepos[1. Browser find on page. Yes[1. 81]Yes. 1. Browser/email save images. Yes. Yes[1. 83]Yes[1. Yes? Yes. Browser/email save PDFs. Yes. Yes[6. 4]Yes[1. Yes. Yes. Yes. Browser save audio/video. Yes, but only links, not embedded media. Yes (embedded media not supported)Yes. Yes. Browser save page. Yes, Google Chrome 5. Offline Reading List; [1. Yes[1. 92]Yes? Browser save any file. No,[1. 93] 3rd party software[1. When an app that can handle/open the filetype is installed (excluding audio/video - requires 3rd party software[1. Yes. Browser force enable zoom. No, not working anymore on Android 4. Yes[1. 98]Yes, via accessibility settings. Yes,via accessibility settings?? Browser text reflow[1. No, removed on Android 4. Only on pages with reader mode available; [2. Only on pages available on reading view on 8. Yes[2. 05] 1. 0+ Only in reader mode. No. No. Browser Reader Mode. No,[2. 06] 3rd party software[2. Yes. No[2. 11]Browser file upload. Limited. Yes. 4. 2+[2. Yes. 1. 0. 7. 1. 6+[2. Browser form navigation. Next button[2. 15]Previous, Next, Auto. Fill, and Done buttons[2. Yes. Yes[2. 13]?? Browser private browsing mode. Yes. 1. 1. 6. 2. 7+[2. Offline web apps. Yes[2. 22]Yes[2. 23][2. No? HTTP Live Streaming. No?[2. 30]Web. RTCYes[2. No. No. No. No. Communication and connectivity[edit]Communication and connectivity. Feature. Androidi. OSWindows 1. 0 Mobile. Black. Berry 1. 0Tizen. Sailfish OSUnified Inbox. No,[2. 33] but 3rd party apps available[2. Yes. 7. 5+[2. 35]Yes. Yes. Yes. Email sync protocols supported. POP3, IMAP, MAPIPOP3, IMAP, MAPI, Active. Sync[2. 36]POP3, IMAP, MAPI, Active. Sync. BES, BIS, Push e- mail, 1. POP3, IMAP, Active. Sync. POP3, IMAPPOP3, IMAP, Active. Sync. Non- carrier- based integrated messaging. Google Hangouts. 5+ (i. Message)[2. 37]Skype[2. BBM? 3rd party software. Visual voicemail. Yes. Yes[2. 40]Yes?? Call log duration. Yes[2. 41]Yes[2. 42]8. Yes[2. 44]? Yes. Multiple mobile phones per contact. Yes. Yes. Yes. Yes? Yes. Contact groups. Instagram, Facebook’s hotter, snootier subsidiary, may have a massive data breach on its hands. This week, a security flaw within Instagram allowed hackers to. Latest trending topics being covered on ZDNet including Reviews, Tech Industry, Security, Hardware, Apple, and Windows. Latest Topics | ZDNet. At a time when Australia continues to cut money from the public service, particularly anything focused on science or education, a space agency proposal smells more like pork than rocket fuel. Chris Duckett in Innovation. Instagram Done Got Hacked. Instagram, Facebook’s hotter, snootier subsidiary, may have a massive data breach on its hands. This week, a security flaw within Instagram allowed hackers to assemble a database of what appeared to be verified users’ contact information—some of those affected purportedly being celebrities and politicians. According to the Verge, Instagram now says the known scope of the breach has expanded to include at least some unverified Instagrammers.“.. We recently discovered a bug on Instagram that could be used to access some people’s email address and phone number even if they were not public,” Instagram CTO Mike Krieger wrote in a blog post. No passwords or other Instagram activity was revealed. We quickly fixed the bug, and have been working with law enforcement on the matter. Although we cannot determine which specific accounts may have been impacted, we believe it was a low percentage of Instagram accounts.”“We are very sorry this happened,” Krieger added. As the Daily Beast reported last week, the unknown hackers behind the breach claim to have compromised six million accounts and set up a website called “Doxagram,” which allegedly offered access to phone numbers, email addresses or both for 1,0. Instagram accounts at $1. While a few of the addresses were public information, “many did not return any relevant Google results, implying they were obtained from some private source.” The Beast was able to confirm some of the leaked accounts had valid contact information; the site was later taken offline. Per the Verge, cybersecurity firm Rep. Knight said supposed contact information for a number of celebrities featured on Doxagram was circulating on the dark web, ranging from Hollywood celebs like Emma Watson and Leonardo Di. Caprio to musician Harry Styles and boxer Floyd Mayweather. The Beast claimed the site even purported to have contact info behind President Donald Trump’s official Instagram profile, which was managed by White House social media director Dan Scavino. In addition to potentially exposing users to harassment, the breach could allow hackers to target them for social engineering attacks which could compromise their accounts. Instagram’s security hole may be linked to an incident on August 2. Selena Gomez—the most- followed user on the site—and posted nude photographs of Justin Bieber. Data breaches are not the only major problem reported at the social- media giant in recent days. On Friday, Mashable reported the site’s staff is rife with individuals willing to verify Instagram accounts for prices “anywhere from a bottle of wine to $1. Working with headphones on usually means you’d rather not be bothered, but sometimes it means you’re just listening to something while you work. If you want to be.Abstract. 1A randomised, prospective, multicenter phase III trial of adjuvant chemotherapy with gemcitabine vs. PC)J. Langrehr, H. Oettle, S. Post, K. Gellert, K. Ridwelski, H. Schramm, C. Zülke, G. Fahlke, L. Roll, P. Tabtight professional, free when you need it, VPN service. 1. A randomised, prospective, multicenter phase III trial of adjuvant chemotherapy with gemcitabine vs. observation in patients with resected pancreatic cancer (PC). Statistical Techniques | Statistical Mechanics. Neuhaus, H. Riess Charitè – Universitätsmedizin Berlin - Campus Virchow Klinikum; Ruprecht- Karls- Universitüt, Mannheim; Oskar- Ziethen- Krankenhaus, Berlin; Otto- von- Guericke- Universität, Magdeburg; Wald- Klinikum, Gera; Universität Regensburg, Regensburg; for the German pancreatic cancer study group (supported by AIO; CAO; Deutsche Krebsgesellschaft E. V.)Background. Chemotherapy with Gemcitabine (G) is standard therapy in advanced, inoperable PC. The value of adjuvant therapy has not been clearly defined yet, and no randomised trial with G in the adjuvant setting is available. Methods. This study was designed to evaluate the efficacy and toxicity of adjuvant G in patients (pts) with resectable pancreas cancer. Within 6 weeks after operation, pts were randomised to receive G or observation (O) after stratification for positive or negative resection margins, nodal tumor involvement and tumor stage. G was administered at a dosage of 1 g/m. Pts in the O arm received no specific postoperative treatment, but were followed similar to the G group. Primary endpoint was disease free survival (DFS), secondary endpoints included overall survival (OS) and side effects in both groups. The study was powered to detect a significant difference with 9. Results. Between 0. Excluding 1. 2 ineligible pts, 1. G and 1. 77 to O. Pts characteristics were well balanced (G/O) with regard to median age (6. T3 + T4 8. 6/8. 6%), nodal status (N neg: 2. N pos: 7. 1/7. 3%), resection margin R0: 8. R1: 1. 9/1. 6%). February 2. DFS. Analysis shows a difference in median DFS [G: 1. O: 7. 5 m, p < 0. Subgroup analysis demonstrated increased DFS in pts with (n = 6. Grade 3/4 toxicities per pt were: leucocytes (G: 8. O: 0%), platelets (G: 2. O: 0%), diarrhea (G: 2. O: 1. 1%), nausea (G: 4. O: 0. 6%). Conclusion. Preliminary results demonstrate an increased DFS in pts with resected PC when treated with G for 6 months after resection. The most recent survival data will be presented at the meeting. Final results will be expected in late 2. The impact of margins on outcome following hepatic resection for colorectal metastasis. Chandrakanth Are, MD, Mithat Gonen, Ph. D, Kathleen Zazzali, DO, Ronald P. Dematteo, MD, William R. Jarnagin, MD, Yuman Fong, MD, Leslie H. Blumgart, MD, Michael D.’ Angelica, MDMemorial Sloan Kettering Cancer Centre, New York, NYIntroduction. The optimal margin width in hepatic resection for colorectal metastasis (CRM) is unclear. The aim of this study was to analyze the impact of margins on survival in a large single institution series and ascertain the optimal margin width. Material and Methods. All patients undergoing hepatic resection for CRM from 1. The effect of tumor related and technical factors on margin width and survival was analyzed. The associations between clinical risk factor and margins were tested using Cochran- Armitage trend test. Survival curves were estimated using Kaplan- Meier methods and compared with log- rank test. Multivariate analysis was done using Cox regression. Results. A total of 1. Analysis of margin width as a continuous variable suggested the following grouping: Group I: involved and < 1 mm (n = 1. Group II- 1–1. 0 mm (n = 5. Group III- > 1. Bilateral resections (p = < 0. There was a statistically significant difference in median survival between the three groups: 3. Groups I, II and III respectively (p < 0. Margin width retained its significance (p < 0. After adjustment, survival in Group III was significantly better than either Group I or II (p < 0. Group I and Group II (p = 0. Conclusion. This study provides evidence that margin width of > 1 cm is optimal and an independent predictor of survival following hepatic resection for CRM. However subcentimeter resections are also associated with acceptable survival and therefore should not preclude patients from undergoing resection. Impact of Margins, Biological and Technical Factors on Survivaln. Median Survival (months)Uni- variate p. Multi variate p. Less than lobectomy vs Lobectomy or more. NSUnilateral resection vs Bilateral resection. Size < 5 cm vs Size > 5 cm. Node negative primary vs Node positive primary. DFI > 1. 2 months vs DFI < 1. NSMetachronous vs Synchronous. NSMargin > 1 cm vs Negative margin 1–1. Positive margin. 34. C- acetate is superior to. F- fluorodeoxyglucose (FDG) positron emission tomography (PET) in evaluating patients with hepatocellular carcinoma: Results of a pilot trial. Sean C. Glasgow, MD, Farrokh Dehdashti, MD, Barry A. Siegel, MD, William C. Chapman, MDWashington University, St. Louis, MOIntroduction. Although FDG- PET is widely accepted for the evaluation for metastatic tumors within the liver, its sensitivity for detecting hepatocellular carcinoma (HCC) is poor. Adequate pretransplantation staging of patients with HCC is crucial to assure optimization of scarce resources, and determination of recurrent disease post- ablation is often difficult using standard tomographic imaging. C- acetate (AC) may be a better PET radiopharmaceutical for the detection of HCC; however, extensive data providing direct comparison between the two tracers are lacking and the potential impact of AC- PET in the management of patients with HCC is unknown. Methods. Adult patients with either a history of biopsy- proven or suspected HCC (AFP > 2. L or arterially- enhancing hepatic mass) were prospectively enrolled in this IRB- approved trial. Subjects underwent synchronous FDG- and AC- PET, and the imaging studies were interpreted independently in a blinded manner by two nuclear radiologists. Further evaluations and therapies were performed at the discretion of the treating surgeon. Participants were then followed to determine whether either functional imaging test influenced treatment decisions. Results. Thirty patients participated, with a total of 4. HCC lesions greater than 1 cm diameter evaluated by both FDG- and AC- PET. AC- PET was positive in 3. FDG- PET was positive in only 1. Only one lesion was undetectable by either PET modality (false- negative rate 3%). The sensitivity of AC- PET in patients with normal serum AFP levels was 7. FDG- PET. In seven patients evaluated following HCC- specific treatment (RF ablation or transplantation), the specificity of AC- PET was 1. Additionally, AC- PET was the sole diagnostic modality to detect HCC in two subjects: HCC recurrence following liver transplantation in one patient allowed timely RF ablation, while HCC metastatic to the adrenal gland was detected in a second patient. Conclusions. This pilot study demonstrated the utility of AC- PET in the management of patients with HCC, while confirming the lack of sensitivity of standard FDG- PET for this malignancy. The superiority of AC- PET was independent of clinical features such as AFP. AC- PET may have a role in screening certain patients prior to liver transplantation, particularly those beyond UNOS stage 2. It may also prove useful in following disease progression after ablative procedures. Effect of exending- 4 tretment in a minimal islet mass transplant model in streptozotocin- induced diabetic mice. Yong Wang, MD, Jose Avilar, MD, Qi Meirigeng, MD, Barbaro Barbara, Ph. D, Joseph Kuechle, MD, Mark Brown, MD, Enciro Benedetti, MD, Jose Oberholzer, MDUniversity of Illinois at Chicago, Chicago, ILBackground. Exendin- 4 (EX- 4), a long acting agonist of GLP- 1 receptor and potent intestinal insulinotropic hormone, augments insulin secretion in rodent models of diabetes and in human subjects. EX- 4 and GLP- 1 have been demonstrated to promote replication and differentiation of beta- cells in vivo and in vitro. In this study, we examined the effect of EX- 4 on minimal mass islet transplants and the native pancreas of streptozotocin- induced diabetic mice. Methods. Two hundred isogeneic C5. BL6 islets were transplanted under the kidney capsule of streptozotocin- induced diabetic C5. BL6 mice. For the control group, islets were transplanted without EX- 4 treatment. In the treatment group, mice were treated with daily intraperitoneally injection of EX- 4 at 0. Islet function was monitored by daily glycemia and intraperitoneal glucose tolerance test (IPGTT, 2 gram/kg glucose) at week 2 and 4. Google Reader – Google. What will happen to my Google Reader data? All Google Reader subscription data (eg. |
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November 2017
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